Bioconjugate Chemistry
Preformulated, Shelf-Stable, Dendritic Cell-Targeting Nanogel mRNA Vaccine Delivery Platform
2026
DOI / paperEvidence for platforms that move from chemistry to use.
Selected papers and preprints across high-resolution 3D printing, microneedle systems, RNA delivery, carbon architectures, and translational medicine.
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ACS Nano
Engineered 3D-Lattice Microneedle Array Patches for Enhanced Nanovaccine Delivery to Dendritic Cells in Cancer Immunotherapy
2026
DOI / paperAdvanced Materials Technologies
Tunable Applicator for Microneedle-Based Medical Devices
2026
DOI / paperAll Publications
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Showing 23 of 23
Bioconjugate Chemistry
Preformulated, Shelf-Stable, Dendritic Cell-Targeting Nanogel mRNA Vaccine Delivery Platform
Laturski, A. E., Durán, V., Schaar, B. T., Dulay, M. T., Einav, S., DeSimone, J. M.
DOI / paperACS Nano
Engineered 3D-Lattice Microneedle Array Patches for Enhanced Nanovaccine Delivery to Dendritic Cells in Cancer Immunotherapy
Kim, Y. E., Kwak, J. W., Mo, X. W., Nguyen, T. L., Kamat, N. U., Phan, N. M., Shin, H., Soh, H. T., DeSimone, J. M., Kim, J.
DOI / paperAdvanced Materials Technologies
Tunable Applicator for Microneedle-Based Medical Devices
Ilyn, D., Hwang, J., Coates, I. A., Dobson, J., Hung, A. H., Kamat, N. U., Tumbleston, J. R., Dulay, M. T., Jacobson, G. B., DeSimone, J. M.
DOI / paperAdvanced Materials
A 3D-Printed Scaffolded Hydrogel Microneedle Array Biosensor for Real-Time, Continuous Monitoring
Kwak, J. W., Trinh, T., White, A. D., Chen, Y., Eckman, N., Jain, I., Xu, Y., Nguyen, N., Gopalan, D., Kim, Y. E., Kamat, N. U., Tumbleston, J. R., Park, C. H., Yoshikawa, A., Ji, J., Dulay, M. T., Eisenstein, M., Appel, E. A., Kim, J., DeSimone, J. M., Soh, H. T.
DOI / paperAdvanced Materials Technologies
Engineering Ultra-Soft Porous Hydrogel Scaffolds via High-Resolution 3D Printing to Enhance Cell-Based Therapy for Glioblastoma
Garcia-Avila, J., Zhang, Yu., Carlberg, L. E., Stockwell, C., Hwang, J., Dulay, M. T., Hingtgen, S. D., Perry, J. L., DeSimone, J. M.
DOI / paperCarbon
Engineered 3D micro-architected carbon structures via conformal deposition of multifunctional transition metal catalysts
Kuo, H. L., Onffroy, P. R., Chiovoloni, S. P., Williams, L., DeSimone, J. M., Lu, J.
DOI / paperScience Advances
A microneedle device for rapid dermal interstitial fluid sampling
Hung, A. H., Kamat, N. U., Bermudez, A., Boczek, S. M., Garcia-Marques, F. J., Tan, Y. L., Hwang, J., Sinawang, P. D., Ilyin, D., Jacobson, G. B., Demirci, U., Poplack, S. P., Bittere, S. J., DeSimone, J. M.
DOI / paperChemistry of Materials
Fabrication of 3D-Printed Carbon Microarchitected Structures with High Yield from Polyacrylonitrile Composites via Gel Infusion and Pyrolysis
Onffroy, P. R., Lagat, M., Schröder, D., Dobson, J. A., Chiovoloni, S., Bortner, M. J., Lu, J. Q., Saccone, M. A., DeSimone, J. M.
DOI / paperAdvanced Functional Materials
Free-form microfluidic microneedle array patches
Coates, I. A., Driskill, M. M., Rajesh, N. U., Lipkowitz, G., Ilyn, D., Xu, Y., Dulay, M. T., Jacobson, G. B., Tumbleston, J. R., Perry, J. L., Tian, S., DeSimone, J. M.
DOI / paperJournal of Controlled Release
Lyophilized SARS-CoV-2 self-amplifying RNA vaccines for microneedle array patch delivery
Driskill, M. M., Coates, I. A., Hurst, P. J., Rajesh, N. U., Dulay, M. T., Waymouth, R. M., Akahata, W., Matsuda, K., Smith, J. F., Jacobson, G. B., Perry, J. L., Tian, S., DeSimone, J. M.
DOI / paperBioconjugate Chemistry
Transfection via RNA-Based Nanoparticles: Comparing Encapsulation vs Adsorption Approaches of RNA Incorporation
Laturski, A. E., Dulay, M. T., Perry, J. L., DeSimone, J. M.
DOI / paperJACS Au
Opportunities at the Intersection of 3D Printed Polymers and Pyrolysis for the Microfabrication of Carbon-Based Energy Materials
Onffroy, P. R., Chiovoloni, S., Kuo, H. L., Saccone, M. A., Lu, J. Q., DeSimone, J. M.
DOI / paperProceedings of the National Academy of Sciences
High-resolution stereolithography: Negative spaces enabled by control of fluid mechanics
Coates, I. A., Pan, W., Saccone, M. A., Lipkowitz, G., Ilyn, D., Driskill, M. M., Dulay, M. T., Frank, C. W., Shaqfeh, E. S. G., DeSimone, J. M.
DOI / paperAdvanced Materials
3D-Printed Latticed Microneedle Array Patches for Tunable and Versatile Intradermal Delivery
Rajesh, N., Hwang, J., Xu, Y., Saccone, M. A., Hung, A. H., Hernandez, R. A. S., Coates, I. A., Driskill, M., Dulay, M., Jacobson, G. B., Tian, S., Perry, J. L., DeSimone, J. M.
DOI / paperProceedings of the National Academy of Sciences
Growing Three-Dimensional Objects with Light
Lipkowitz, G., Saccone, M. A., Panzer, M. A., Coates, I. A., Hsiao, K., Ilyn, D., Kronenfeld, J. M., Tumbleston, J. R., Shaqfeh, E. S. G., DeSimone, J. M.
DOI / paperNature
Roll-to-Roll, High-Resolution 3D Printing of Shape-Specific Particles
Kronenfeld, J. M., Rother, L., Saccone, M. A., Dulay, M. T., DeSimone, J. M.
DOI / paperGreen Chemistry
Review of High-Performance Sustainable Polymers in Additive Manufacturing
Chyr, G., DeSimone, J. M.
DOI / paperJACS Au
3D-printed microarray patches for transdermal applications
Rajesh, N. U., Coates, I., Driskill, M. M., Dulay, M. T., Hsiao, K., Ilyin, D., Jacobson, G. B., Kwak, J. W., Lawrence, M., Perry, J., Shea, C. O., Tian, S., DeSimone, J. M.
DOI / paperScience Advances
Single-digit-micron-resolution continuous liquid interface production (CLIP) 3D printer
Hsiao, K., Lee, B., Samuelsen, T., Lipkowitz, G., Ilyin, D., Shih, A., Dulay, M. T., DeSimone, J. M.
DOI / paperScience Advances
Injection continuous liquid interface production of 3D objects
Lipkowitz, G., Samuelsen, T., Hsiao, K., Lee, B., Dulay, M. T., Coates, I., Lin, H., Pan, W., Toth, G., Tate, L., Shaqfeh, E. S. G., DeSimone, J. M.
DOI / paperAdditive Manufacturing
Characterization of a 30-micron pixel size CLIP-based 3D printer and its enhancement through dynamic printing optimization
Lee, B., Hsiao, K., Lipkowitz, G., Samuelsen, T., Tate, L., DeSimone, J. M.
DOI / paperJournal of Controlled Release
3D printed drug-loaded implantable devices for intraoperative treatment of cancer
Hagan IV, C. T., Bloomquist, C., Warner, S., Knape, N. M., Kim, I., Foley, H., Wagner, K. T., Mecham, S., DeSimone, J.
DOI / paperProceedings of the National Academy of Sciences
Transdermal vaccination via 3D printed microneedle induces potent humoral and cellular immunity
Caudill, C., Iliadis, K., Perry, J., Mecham, S., Tian, S., DeSimone, J. M.
DOI / paper